ADSL Monoclonal Antibody (OTI2D10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA525263-Each-of-1 | In Stock | ₹ 52,287.50 |
PIMA525263 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,287.50
GST (18%): ₹ 9,411.75
Total Price: ₹ 61,699.25
Antigen
ADSL
Classification
Monoclonal
Concentration
0.55 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P30566, Q8HXY5
Gene Symbols
Adsl
Immunogen
Full length human recombinant protein of ADSL produced in HEK293T cell
Quantity
100μL
Primary or Secondary
Primary
Target Species
Canine, Cynomolgus Monkey, Human, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI2D10
Conjugate
Unconjugated
Gene
Adsl
Gene Alias
2510006M18Rik; Adenylosuccinase; adenylosuccinate lyase; adenylosuccinate lyase 1; Adl; Adsl; AMPS; argininosuccinase; argininosuccinate lyase; Arginosuccinase; ASAL; ASase; ASL; null; test; unnamed protein product
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
101864843, 158, 315150, 474499
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- ADSL (adenylosuccinate lyase), also known as AMPS, ASL or ASASE, is a 484 amino acid protein that is involved in both purine biosynthesis and in the formation of adenosine monophosphate (AMP) from inosine monophosphate
- Expressed ubiquitously, ADSL catalyzes two key reactions in AMP biosynthesis, namely the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and the subsequent removal of fumarate from adenylosuccinate to yield AMP
- Defects in the gene encoding ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency), an autosomal recessive disorder characterized by epilepsy, growth retardation and muscular wasting
- Multiple isoforms of ADSL exist due to alternative splicing events.