PIMA525265

PUS7 Monoclonal Antibody (OTI4C6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA525265-Each-of-1 In Stock ₹ 52,198.50

PIMA525265 - Each of 1

₹ 52,198.50

In Stock

Quantity

1

Base Price: ₹ 52,198.50

GST (18%): ₹ 9,395.73

Total Price: ₹ 61,594.23

Antigen

PUS7

Classification

Monoclonal

Concentration

0.6 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q96PZ0

Gene Symbols

PUS7

Immunogen

Full length human recombinant protein of PUS7 produced in HEK293T cell

Quantity

100μL

Primary or Secondary

Primary

Target Species

Canine, Human, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunocytochemistry, Western Blot

Clone

OTI4C6

Conjugate

Unconjugated

Gene

PUS7

Gene Alias

C330017I15Rik; FLJ20485; Kiaa1897; pseudouridine synthase 7; pseudouridylate synthase 7; pseudouridylate synthase 7 (putative); pseudouridylate synthase 7 homolog; pseudouridylate synthase 7 homolog (S. cerevisiae); PUS7; RGD1307054

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100856353, 296751, 54517

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Pseudouridylate synthase that catalyzes pseudouridylation of RNAs (PubMed:28073919, PubMed:29628141, PubMed:30778726)
  • Acts as a regulator of protein synthesis in embryonic stem cells by mediating pseudouridylation of RNA fragments derived from tRNAs (tRFs): pseudouridylated tRFs inhibit translation by targeting the translation initiation complex (PubMed:29628141)
  • Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3' (PubMed:28073919)
  • In addition to mRNAs and tRNAs, binds other types of RNAs, such as snRNAs, Y RNAs and vault RNAs, suggesting that it can catalyze pseudouridylation of many RNA types (PubMed:29628141)
  • [UniProt]