PIMA525406

ZFP36 Monoclonal Antibody (OTI1A2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA525406-Each-of-1 In Stock ₹ 55,714.00

PIMA525406 - Each of 1

₹ 55,714.00

In Stock

Quantity

1

Base Price: ₹ 55,714.00

GST (18%): ₹ 10,028.52

Total Price: ₹ 65,742.52

Antigen

ZFP36

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P22893, P26651

Gene Symbols

Zfp36

Immunogen

Full length human recombinant protein of ZFP36 produced in HEK293T cell

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI1A2

Conjugate

Unconjugated

Gene

Zfp36

Gene Alias

G0/G1 switch regulatory protein 24; G0S24; GOS24; growth factor-inducible nuclear protein NUP475; mRNA decay activator protein ZFP36; Nup475; RNF162A; Tax interacting protein; TIS11; TIS11A; TIS11D; TISII; TNF alpha inhibitor; TPA-induced sequence 11; Tristetraprolin; tristetraprolin; LOW QUALITY PROTEIN: mRNA decay activator protein ZFP36; tristetraproline; TTP; Zfp36; zfp-36; ZFP36 ring finger protein; zinc finger protein 36; zinc finger protein 36 homolog; zinc finger protein 36, C3H type, homolog; zinc finger protein, C3H type, 36 homolog

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22695, 7538

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors
  • Knockdown of ZFP36 increased both cognate macrophage gene mRNAs and inflammatory tumor necrosis factor protein release
  • Overexpression of ZFP36 resulted in decreased levels of the same genes supporting its role in regulating macrophage gene expression
  • Multiple phosphorylation sites in ZFP36 in mammalian cells were reported
  • ZFP36 can be phosphorylated by JNK as well as by the other members of the greater MAP kinase family
  • Gene expression profiling predicts clinical outcome of prostate cancer
  • Inappropriate ZFP36 production may be one factor that contributes to higher rheumatoid arthritis disease activity.