PIMA525436

S100A12 Monoclonal Antibody (OTI1D1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA525436-Each-of-1 In Stock ₹ 52,198.50

PIMA525436 - Each of 1

₹ 52,198.50

In Stock

Quantity

1

Base Price: ₹ 52,198.50

GST (18%): ₹ 9,395.73

Total Price: ₹ 61,594.23

Antigen

S100A12

Classification

Monoclonal

Concentration

0.68 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P80511

Gene Symbols

S100A12

Immunogen

Full length human recombinant protein of S100A12 produced in HEK293T cell

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI1D1

Conjugate

Unconjugated

Gene

S100A12

Gene Alias

CAAF1; CAGC; Calcitermin; calcium-binding protein in amniotic fluid 1; calgranulin C; calgranulin-C; CGRP; EN RAGE; ENRAGE; EN-RAGE; Extracellular newly identified RAGE-binding protein; migration inhibitory factor-related protein 6; MRP6; MRP-6; Neutrophil S100 protein; p6; Protein S100 A12; protein S100-A12; S100 calcium binding protein A12; S100 calcium-binding protein A12; S100 calcium-binding protein A12 (calgranulin C); S100A12

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6283

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs
  • S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation
  • S100A12 is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities
  • S100A12 is also a ligand for RAGE
  • Interaction with RAGE on mononuclear phagocytes, lymphocytes and endothelium triggers cellular activation
  • Nuclear factor kappa B, a key transcription factor for inflammatory events, is activated by S100A12/RAGE
  • S100A12 has also been shown to have anti-microbial properties.