LIMK1 Monoclonal Antibody (OTI6B4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA525569-Each-of-1 | In Stock | ₹ 55,714.00 |
PIMA525569 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,714.00
GST (18%): ₹ 10,028.52
Total Price: ₹ 65,742.52
Antigen
LIMK1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P53667, P53668, P53669
Gene Symbols
LIMK1
Immunogen
Full length human recombinant protein of LIMK1 produced in HEK293T cell
Quantity
100μL
Primary or Secondary
Primary
Target Species
Canine, Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG2a
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI6B4
Conjugate
Unconjugated
Gene
LIMK1
Gene Alias
EC 2.7.11.1; kinase LIMK1; KIZ-1; LIM domain kinase 1; lim kinase 1; LIM motif-containing protein kinase; LIM motif-containing protein kinase 1; LIM-domain containing protein kinase 1; LIM-domain containing, protein kinase; LIM-domain containing, protein kinase 1; Limk; LIMK1; LIMK-1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16885, 3984, 489800, 65172
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- LIMK1 is a serine/threonine kinase involved in regulation of actin cytoskeletal changes via phosphorylation of cofilin
- LIMK1 has also been implicated in brain development
- LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers
- Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions
- LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain
- LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development
- LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome.