ITFG2 Monoclonal Antibody (OTI3A3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA525576-Each-of-1 | In Stock | ₹ 52,198.50 |
PIMA525576 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,198.50
GST (18%): ₹ 9,395.73
Total Price: ₹ 61,594.23
Antigen
ITFG2
Classification
Monoclonal
Concentration
0.84 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q969R8
Gene Symbols
ITFG2
Immunogen
Full length human recombinant protein of ITFG2 produced in HEK293T cell
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI3A3
Conjugate
Unconjugated
Gene
ITFG2
Gene Alias
2700050P07Rik; AI646725; integrin alpha FG-GAP repeat containing 2; integrin-alpha FG-GAP repeat-containing protein 2; integrin-alpha FG-GAP repeat-containing protein 2; KICSTOR complex protein ITFG2; ITFG2; KICSTOR complex protein ITFG2; MDS028; RGD1311944
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
362441, 55846
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway
- Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases
- Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids
- In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated
- The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.