PTP1B Monoclonal Antibody (OTI2G3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA525616-Each-of-1 | In Stock | ₹ 55,358.00 |
PIMA525616 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,358.00
GST (18%): ₹ 9,964.44
Total Price: ₹ 65,322.44
Antigen
PTP1B
Classification
Monoclonal
Concentration
0.68 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P18031
Gene Symbols
PTPN1
Immunogen
Full length human recombinant protein of PTPN1 produced in HEK293T cell
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI2G3
Conjugate
Unconjugated
Gene
PTPN1
Gene Alias
CPTP1; EC 3.1.3.48; EGK_02300; hgnc9642; KIAA0283; protein tyrosine phosphatase 1B; protein tyrosine phosphatase non-receptor type 1; protein tyrosine phosphatase, non-receptor type 1; protein tyrosine phosphatase, placental; protein-protein-tyrosine phosphatase HA2; protein-tyrosine phosphatase 1B; Protein-tyrosine phosphatase HA2; PTN1; Ptp; PTP1B; PTP-1B; ptp1b protein; PTP-HA2; Ptpn1; RP5-1121H13.2; RPTPrho; tyrosine phosphatase 1b; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 1; wu:fk54h03
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5770
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- PTP1B (PTPN1) is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response
- It mediates dephosphorylation of EIF2AK3/PERK and in turn inactivates the protein kinase activity of EIF2AK3/PERK
- PTP1B also plays a role in CKII- and p60c-src-induced signal transduction cascades
- It regulates the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion
- PTP1B also regulates the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.