Aminoacylase Monoclonal Antibody (OTI1D4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA525617-Each-of-1 | In Stock | ₹ 52,198.50 |
PIMA525617 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,198.50
GST (18%): ₹ 9,395.73
Total Price: ₹ 61,594.23
Antigen
Aminoacylase
Classification
Monoclonal
Concentration
0.3 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q03154, Q99JW2
Gene Symbols
ACY1
Immunogen
Full length human recombinant protein of ACY1 produced in HEK293 cell
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI1D4
Conjugate
Unconjugated
Gene
ACY1
Gene Alias
1110014J22Rik; ACY IA; ACY IB; ACY1; ACY-1; Acy1a; ACY-1A; Acy1b; ACY-1B; ACY1D; acylase; aminoacylase 1; aminoacylase I; aminoacylase-1; Aminoacylase-1A; aminoacylase-1B; epididymis secretory protein Li 5; HEL-S-5; N-acylamino acid aminohydrolase (Aminoacylase 1); N-acyl-L-amino-acid amidohydrolase
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
109652, 95
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- ACY1 encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids
- This gene is located on chromosome 3p21
- 1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors
- The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes
- Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids
- Alternative splicing of this gene results in multiple transcript variants
- Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene
- A related pseudogene has been identified on chromosome 18.