RFXANK Monoclonal Antibody (OTI2F12), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA525863-Each-of-1 | In Stock | ₹ 52,198.50 |
PIMA525863 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,198.50
GST (18%): ₹ 9,395.73
Total Price: ₹ 61,594.23
Antigen
RFXANK
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O14593
Gene Symbols
RFXANK
Immunogen
Full length human recombinant protein of RFXANK produced in HEK293T cell
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI2F12
Conjugate
Unconjugated
Gene
RFXANK
Gene Alias
ANKRA1; Ankyrin repeat family A protein 1; ankyrin repeat-containing regulatory factor X-associated protein; BLS; DNA-binding protein RFXANK; F14150_1; regulatory factor X associated ankyrin containing protein; regulatory factor X subunit B; Regulatory factor X-associated ankyrin-containing protein; RFXANK; RFXB; RFX-B; RFX-Bdelta4
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8625
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
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Description
- Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system
- The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription
- Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression
- This protein contains ankyrin repeats involved in protein-protein interactions
- Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B
- Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity.