PIMA527076
TRIM56 Monoclonal Antibody (OTI8E12), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA527076-Each-of-1 | In Stock | ₹ 52,554.50 |
PIMA527076 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,554.50
GST (18%): ₹ 9,459.81
Total Price: ₹ 62,014.31
Antigen
TRIM56
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q9BRZ2
Gene Symbols
TRIM56
Immunogen
Human recombinant protein fragment corresponding to amino acids 311-554 of TRIM56 produced in E.coli
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI8E12
Conjugate
Unconjugated
Gene
TRIM56
Gene Alias
E3 ubiquitin-protein ligase TRIM56; RING finger protein 109; RING-type E3 ubiquitin transferase TRIM56; RNF109; TRIM56; tripartite motif containing 56; tripartite motif-containing protein 56
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
81844
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- E3 ubiquitin-protein ligase that plays a key role in innate antiviral immunity (PubMed:21289118)
- In response to pathogen- and host-derived double-stranded DNA (dsDNA), targets STING1 to 'Lys-63'-linked ubiquitination, thereby promoting its homodimerization, a step required for the production of type I interferon IFN-beta
- Independently of its E3 ubiquitin ligase activity, positive regulator of TLR3 signaling
- Potentiates extracellular double stranded RNA (dsRNA)-induced expression of IFNB1 and interferon-stimulated genes ISG15, IFIT1/ISG56, CXCL10, OASL and CCL5/RANTES
- Promotes establishment of an antiviral state by TLR3 ligand and TLR3-mediated chemokine induction following infection by hepatitis C virus (PubMed:22948160)
- [UniProt]