PIMA527138

RAB23 Monoclonal Antibody (OTI2A8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527138-Each-of-1 In Stock ₹ 52,198.50

PIMA527138 - Each of 1

₹ 52,198.50

In Stock

Quantity

1

Base Price: ₹ 52,198.50

GST (18%): ₹ 9,395.73

Total Price: ₹ 61,594.23

Antigen

RAB23

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q9ULC3

Gene Symbols

RAB23

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-234 of RAB23 produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2A8

Conjugate

Unconjugated

Gene

RAB23

Gene Alias

AW545388; DKFZp781H0695; HSPC137; MGC8900; opb; opb2; open brain 2; OTTHUMP00000040021; protein open brain; RAB 23; RAB family small GTP binding protein RAB 23; rab-15; RAB23; RAB23, member RAS oncogene family; ras-related protein Rab-23; RP3-496N17.3

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

51715

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies
  • Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport
  • The process of transporting newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function
  • Rab proteins are also an integral part of endocytic pathways
  • Rab 23, also known as HSPC137, is a 237 amino acid member of the Rab family of proteins and localizes to the cytoplasmic side of the cell membrane
  • Rab 23 is believed to play a role in intracellular protein transportation and signal transduction mediated by small GTPases
  • Mutations in the gene encoding Rab 23 may result in Carpenter syndrome, also known as ACPS2 (acrocephalopolysyndactyly type 2), a condition characterized by obesity, cardiac defects, polysyndactyly and craniosynostosis.