TRMT12 Monoclonal Antibody (OTI5C9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA527177-Each-of-1 | In Stock | ₹ 52,198.50 |
PIMA527177 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,198.50
GST (18%): ₹ 9,395.73
Total Price: ₹ 61,594.23
Antigen
TRMT12
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q53H54
Gene Symbols
TRMT12
Immunogen
Full length human recombinant protein of TRMT12 produced in E.coli
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI5C9
Conjugate
Unconjugated
Gene
TRMT12
Gene Alias
4632406N01Rik; AI449275; alpha-amino-alpha-carboxypropyl transferase TYW2; homolog of yeast tRNA methyltransferase; TRM12; Trmt12; tRNA methyltranferase 12; tRNA methyltranferase 12 homolog; tRNA methyltransferase 12; tRNA methyltransferase 12 homolog; tRNA wybutosine-synthesizing protein 2 homolog; tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase; tRNA-yW synthesizing protein 2; tRNA-yW-synthesizing protein 2; TYW2
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
55039
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- TYW2, also known as TRM12, is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway
- Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome
- TYW2 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation
- TYW2 was found to be amplified in 7 of 8 breast cancers cell lines analyzed, and qPCR analysis of 30 breast tumors showed overexpression of TYW2 mRNA of over 2-fold in 26, suggesting that TYW2 may play a role in breast cancer.