PIMA527225

METTL7A Monoclonal Antibody (OTI4B10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527225-Each-of-1 In Stock ₹ 52,198.50

PIMA527225 - Each of 1

₹ 52,198.50

In Stock

Quantity

1

Base Price: ₹ 52,198.50

GST (18%): ₹ 9,395.73

Total Price: ₹ 61,594.23

Antigen

METTL7A

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q9H8H3

Gene Symbols

METTL7A

Immunogen

Human recombinant protein fragment corresponding to amino acids 34-104 of METTL7A produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI4B10

Conjugate

Unconjugated

Gene

METTL7A

Gene Alias

2210414H16Rik; 3300001H21Rik; Aam-B; methyltransferase like 7A; methyltransferase like 7A1; methyltransferase like 7A-like; methyltransferase-like protein 7A; METTL7A; Mettl7a1; PRO0066; Protein AAM-B; RGD1308407; UbiE1; UNQ1902/PRO4348

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

25840

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MettL7A belongs to the methyltransferase superfamily
  • It is a probable methyltransferase
  • Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor
  • Often methylation occurs on nucleic bases in DNA or amino acids in protein structures
  • DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence
  • DNA methylation may be necessary for normal growth from embryonic stages in mammals
  • When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype
  • Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.