PIMA527337

ZHX2 Monoclonal Antibody (OTI2E11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527337-Each-of-1 In Stock ₹ 52,554.50

PIMA527337 - Each of 1

₹ 52,554.50

In Stock

Quantity

1

Base Price: ₹ 52,554.50

GST (18%): ₹ 9,459.81

Total Price: ₹ 62,014.31

Antigen

ZHX2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q8C0C0, Q9Y6X8

Gene Symbols

ZHX2

Immunogen

Human recombinant protein fragment corresponding to amino acids 595-837 of ZHX2 produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG2b

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2E11

Conjugate

Unconjugated

Gene

ZHX2

Gene Alias

AFP regulator 1; AFR1; Afr-1; alpha fetoprotein regulation 1, adult; alpha-fetoprotein regulator 1; KIAA0854; LOW QUALITY PROTEIN: zinc fingers and homeoboxes protein 2; mKIAA0854; Raf; Regulator of AFP; transcription factor ZHX2; Zhx2; Zinc finger and homeodomain protein 2; zinc fingers and homeoboxes 2; zinc fingers and homeoboxes protein 2; zinc-fingers and homeoboxes 2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22882, 387609

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA)
  • ZHX1-3 are ubiquitously expressed proteins expressed in various tissues
  • They act as transcriptional repressors and localize to the nucleus
  • The ZHX proteins contain two Cys(2)-His(2)-type zinc-finger motifs and five homeodomains (HDs)
  • These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other
  • However, this dimerization is not required for repressor activity
  • Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).