PIMA527489
FOLR3 Monoclonal Antibody (OTI6C1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA527489-Each-of-1 | In Stock | ₹ 54,201.00 |
PIMA527489 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 54,201.00
GST (18%): ₹ 9,756.18
Total Price: ₹ 63,957.18
Antigen
FOLR3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P41439
Gene Symbols
FOLR3
Immunogen
Full length human recombinant protein of FOLR3 produced in E.coli
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI6C1
Conjugate
Unconjugated
Gene
FOLR3
Gene Alias
Folate receptor 3; folate receptor 3 (gamma); folate receptor gamma; FOLR3; FR gamma; FR- gamma; FR-G; FR-gamma; gamma-hFR
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2352
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Folate is an essential vitamin that must be obtained from food intake through intestinal absorption in mammals
- Folate and reduced folic acid derivatives bind to the folate receptor (FR) family, which mediates the endocytosis of 5-methyltetrahydrofolate into the cell
- The folate receptors consist of five members, alpha, beta, gamma, gamma' (which is produced by alternative splicing) and delta
- beta-FR is attached to the membrane by a GPI anchor and is expressed in malignant tissues of epithelial and nonepithelial origin
- gamma-FR is expressed in tissues of hematopoietic origin, such as spleen, thymus and bone marrow
- The expression pattern of delta-FR is elusive, which suggests that it is highly restricted both spatially and temporally
- The alpha isoform of the folate receptor is used as a highly selective tumor marker and may be targeted for the delivery of therapeutic compounds to tumor cells by coupling to derivatives of folic acid.