CD45RC Monoclonal Antibody (C455.1F), Biotin, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA528673-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA528673 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
CD45RC
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with sucrose and <0.1% sodium azide
Gene Accession No.
P06800
Gene Symbols
Ptprc
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
19264
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry
Clone
C455.1F
Conjugate
Biotin
Gene
Ptprc
Gene Alias
B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Host Species
Rat
Quantity
1 mL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor
- It acts as a positive regulator of T-cell coactivation upon binding to DPP4
- The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first
- Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN
- Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis.