AFP Recombinant Rabbit Monoclonal Antibody (003), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA529006-Each-of-1 | In Stock | ₹ 43,832.50 |
PIMA529006 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,832.50
GST (18%): ₹ 7,889.85
Total Price: ₹ 51,722.35
Antigen
AFP
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P02771
Gene Symbols
AFP
Immunogen
Recombinant Human AFP/alpha-fetoprotein protein (Met1-Val609)
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Immunoprecipitation, Western Blot
Clone
003
Conjugate
Unconjugated
Gene
AFP
Gene Alias
a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
174
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This antibody has specificity for Human AFP/alpha-fetoprotein
- AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life
- AFP expression in adults is often associated with hepatoma or teratoma
- However, hereditary persistence of AFP may also be found in individuals with no obvious pathology
- The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4
- AFP is found in monomeric, dimeric, and trimeric forms
- AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin
- The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly
- High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.