IL-6 Receptor Recombinant Rabbit Monoclonal Antibody (033), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA529721-Each-of-1 | In Stock | ₹ 42,364.00 |
PIMA529721 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,364.00
GST (18%): ₹ 7,625.52
Total Price: ₹ 49,989.52
Antigen
IL-6 Receptor
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P08887, P22272, P22273
Gene Symbols
IL6R, Il6ra
Immunogen
Recombinant Mouse IL-6R/CD126 protein (Ile44-Glu357)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Western Blot
Clone
033
Conjugate
Unconjugated
Gene
IL6R
Gene Alias
CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
16194, 24499, 3570
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This antibody has specificity for Mouse IL-6R/CD126
- Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor
- This gene encodes a subunit of the interleukin 6 (IL6) receptor complex
- Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response
- The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines
- Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer
- Alternatively spliced transcript variants encoding distinct isoforms have been reported
- A pseudogene of this gene is found on chromosome 9.