p53R2 Monoclonal Antibody (11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA529777-Each-of-1 | In Stock | ₹ 32,485.00 |
PIMA529777 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,485.00
GST (18%): ₹ 5,847.30
Total Price: ₹ 38,332.30
Antigen
p53R2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q7LG56
Gene Symbols
Rrm2b
Immunogen
Recombinant Human RRM2B/P53R2 Protein (Met1-Phe351)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Applications
ELISA
Clone
11
Conjugate
Unconjugated
Gene
Rrm2b
Gene Alias
MTDPS8A; MTDPS8B; p53-inducible ribonucleotide reductase small subunit 2 homolog; p53-inducible ribonucleotide reductase small subunit 2 short form beta; p53-inducible ribonucleotide reductase small subunit 2-like protein; p53R2; Ribonucleoside-diphosphate reductase subunit M2 B; ribonucleotide reductase M2 B (TP53 inducible); ribonucleotide reductase regulatory TP53 inducible subunit M2B; RRM2B; TP53-inducible ribonucleotide reductase M2 B
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
50484
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- This antibody has specificity for Human RRM2B/P53R2
- The p53 tumor-suppressor gene integrates numerous signals that control cell life and death
- Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered
- p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase
- p53R2 is induced by the reagents, μgtraviolet and -gamma-irradiation that cause DNA damages
- The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA
- The isoform of the p53 family member p73 also induces p53R2 expression
- p53R2 is an important target of p53 for tumor suppression.