ACVR1B Monoclonal Antibody (4E1C1F12), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA530036-Each-of-1 | In Stock | ₹ 32,485.00 |
PIMA530036 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,485.00
GST (18%): ₹ 5,847.30
Total Price: ₹ 38,332.30
Antigen
ACVR1B
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P36896
Gene Symbols
ACVR1B
Immunogen
Recombinant Human ALK4 protein (Met1-Glu126)
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA
Clone
4E1C1F12
Conjugate
Unconjugated
Gene
ACVR1B
Gene Alias
6820432J04; activin A receptor type 1B; activin A receptor type IB; activin A receptor, type 1B; activin A receptor, type IB; activin A receptor, type II-like kinase 4; activin receptor type IB; Activin receptor type-1B; activin receptor-like kinase 4; ACTRI; ActRIB; ActR-IB; ACVR1A; Acvr1b; ACVRLK2; ACVRLK4; ALK2; Alk4; ALK-4; FOP; Serine/threonine-protein kinase receptor R2; SKR1; SKR2; TSRI
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
91
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- This antibody has specificity for Human ACVR1B/ALK-4
- ACVR1B is a serine/threonine kinase involved in signal transduction and cellular communication
- Several truncated ACVR1B isoforms have been reported to be exclusively expressed in human pituitary tumors
- Mutations of ACVR1B have been observed in pancreatic adenocarcinomas
- Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors
- ACVR1B encodes activin A type IB receptor, composed of 11 exons
- Alternative splicing and alternative polyadenylation result in 3 fully described transcript variants
- The mRNA expression of variants 1, 2, and 3 is confirmed, and a potential fourth variant contains an alternative exon 8 and lacks exons 9 through 11, but its mRNA expression has not been confirmed.