BMP-2 Monoclonal Antibody (23), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA530112-Each-of-1 | In Stock | ₹ 32,485.00 |
PIMA530112 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,485.00
GST (18%): ₹ 5,847.30
Total Price: ₹ 38,332.30
Antigen
BMP-2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P12643, P21274, P49001
Gene Symbols
BMP2
Immunogen
Recombinant Human BMP-2 Protein (Gln283-Arg396)
Quantity
100μL
Primary or Secondary
Primary
Target Species
Canine, Human, Mouse, Rat, Rhesus Monkey
Product Type
Antibody
Applications
ELISA
Clone
23
Conjugate
Unconjugated
Gene
BMP2
Gene Alias
2610024H22Rik; AI467020; AL117858; AW546137; BB189135; BDA2; BMP; BMP2; BMP-2; BMP2A; BMP-2A; BMPRII; BMPR-II; Bone morphogenetic protein; Bone morphogenetic protein 2; bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A); bone morphogenetic protein 2A; H-BMP-2; morphogen
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
12156, 29373, 477162, 650, 718330
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- This antibody has specificity for Human BMP-2
- Bone Morphogenic Proteins (BMP) are members of the TGF-beta superfamily that affect bone and cartilage formation (Hogan 1996, Reddi 1998 and Francis-West et al
- 1999)
- Mature BMPs are 30-38 kDa proteins that assume a TGF-beta -like cysteine knot configuration
- Lovostatin increases bone formation by turning on the bmp-2 gene (Mundy et al
- 1999)
- BMPs stimulate the production of specific bone matrix proteins and alter stromal cell and osteoclast proliferation (Macias et al
- 1999, Lecanda et al
- 1997)
- BMPs may also be an important factor for development of the viscera, with roles in cell proliferation, apoptosis, differentiation, and morphogenesis (Hogan 1996, Dale and Wardle 1999)
- BMPs appear to be responsible for normal dorsal/ventral patterning
- Like TGF-beta, BMPs bind to a type II receptor, which then recruits the transducing type I receptor unit, activating the Smad protein signaling pathway (Massague 1994, Derynck 1997, Attisano 1993).