PIMA530158
CD177 Recombinant Rabbit Monoclonal Antibody (021), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA530158-Each-of-1 | In Stock | ₹ 41,919.00 |
PIMA530158 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,919.00
GST (18%): ₹ 7,545.42
Total Price: ₹ 49,464.42
Antigen
CD177
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q8N6Q3
Gene Symbols
CD177
Immunogen
Recombinant Human CD177/PRV-1/PRV1 Protein (Met1-Gly407)
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA
Clone
021
Conjugate
Unconjugated
Gene
CD177
Gene Alias
1190003K14Rik; CD177; CD177 antigen; CD177 molecule; cell surface receptor; HNA2A; HNA-2a; Human neutrophil alloantigen 2a; NB1; NB1 glycoprotein; NB1 GP; Pdp3; Polycythemia rubra vera protein 1; PRV1; PRV-1; RGD1562941; UNQ595/PRO1181
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
57126
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This antibody has specificity for Human CD177/PRV-1/PRV1
- CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils
- Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application
- Ligand of CD177 has been identified as CD31 (PECAM-1)
- CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule
- The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).