ENO1 Recombinant Rabbit Monoclonal Antibody (063), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA530367-Each-of-1 | In Stock | ₹ 45,078.50 |
PIMA530367 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,078.50
GST (18%): ₹ 8,114.13
Total Price: ₹ 53,192.63
Antigen
ENO1
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P06733
Gene Symbols
ENO1
Immunogen
Recombinant Human ENO1/Enolase 1/alpha-enolase protein (Met1-Lys434)
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Immunocytochemistry, Western Blot
Clone
063
Conjugate
Unconjugated
Gene
ENO1
Gene Alias
0610008I15; 2-phospho-D-glycerate hydrolase; 2-phospho-D-glycerate hydro-lyase; AL022784; alpha enolase; alpha enolase like 1; alpha-enolase; alpha-enolase; c-myc promoter-binding protein-1; c-Myc promoter binding protein; C-myc promoter-binding protein; Eno1; Eno-1; ENO1L1; enoa; Enolase 1; enolase 1, (alpha); enolase 1, alpha non-neuron; enolase-alpha; epididymis secretory protein Li 17; HEL-S-17; MBP-1; MBPB1; MPB1; MPB-1; MYC promoter-binding protein 1; NNE; Non-neural enolase; phosphopyruvate hydratase; Plasminogen-binding protein; PPH; tau-crystallin
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2023
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This antibody has specificity for Human ENO1/Enolase 1/alpha-enolase
- Enolase (2-phosphogly-cerate hydrolyase or phosphopyruvate hydrates) is a glycolytic enzyme that catalyzes the dehydration and conversion of 2-phosphoglycerate to phosphoenolpyruvate
- It comprises three distinct subunits, alpha, beta and gamma
- Non Neuronal Enolase(ENO1) is an isoform of mammalian enolase and is composed of 2 alpha subunits
- The gene for ENO1 also encodes a shorter monomeric structural lens protein, tau-crystallin
- Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses
- May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons
- Stimulates immunoglobulin production.Used as a diagnostic marker for many tumors and, in the heterodimeric form, alpha/gamma, as a marker for hypoxic brain injury after cardiac arrest
- Also marker for endometriosis
- Antibodies against alpha-enolase are present in sera from patients with cancer-associated retinopathy syndrome (CAR), a progressive blinding disease which occurs in the presence of systemic tumor growth, primarily small-cell carcinoma of the lung and other malignancies
- Is identified as an autoantigen in Hashimoto encephalopathy (HE) a rare autoimmune disease associated with Hashimoto thyroiditis (HT)
- HT is a disorder in which destructive processes overcome the potential capacity of thyroid replacement leading to hypothyroidism.