PIMA530436
Cystatin M Recombinant Rabbit Monoclonal Antibody (037), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA530436-Each-of-1 | In Stock | ₹ 41,385.00 |
PIMA530436 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,385.00
GST (18%): ₹ 7,449.30
Total Price: ₹ 48,834.30
Antigen
Cystatin M
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
0
Gene Symbols
CST6
Immunogen
Recombinant Mouse Cystatin E/CST6 protein
Quantity
100μL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Applications
ELISA
Clone
037
Conjugate
Unconjugated
Gene
CST6
Gene Alias
1110017E11Rik; AA960480; CST6; Cstb; cystatin 6; cystatin B; cystatin E/M; cystatin M; cystatin M/E; cystatin N; cystatin-6; Cystatin-B; cystatin-E; Cystatin-M; cysteine proteinase inhibitor; harlequin ichthyosis; harlequin ichthysosis; ichq; N28197; Stefin-B; Stfb
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
73720
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This antibody has specificity for Mouse Cystatin E/CST6
- The cystatin superfamily is a well-established family of cysteine protease inhibitors
- Cystatins A and B (type 1) are mainly intracellular; cystatins C, D, E/M, F, G, S, SN and SA cystatins are extracellular (type 2); and the kininogens are type 3 cystatins which are intravascular proteins
- All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, and some also inhibit legumain family enzymes
- Cystatin SA, cystatin S and cystatin SN are found primarily in saliva
- Cystatin S and SN can also be expressed in tears, urine and seminal fluid
- Cystatin C is a related protein which is expressed in brain, thymus, ovary, epididymis and vas deferens
- Cystatin D protects against proteinases in the oral cavity, while Cystatin E/M and F moderate the inhibition of cathepsin proteins
- The fetuins, part of the cystatin superfamily, are secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors and the response to systemic inflammation
- High molecular weight kininogen (Kininogen HC) and low molecular weight kininogen (Kininogen LC) have varied roles, though they both inhibit the thrombin- and plasmin-induced aggregation of thrombocytes.