IGF1R alpha Recombinant Rabbit Monoclonal Antibody (11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA530512-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA530512 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
IGF1R alpha
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P08069
Gene Symbols
Igf1r
Immunogen
Recombinant Human IGF1R protein (Met1-Asn932)
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA
Clone
11
Conjugate
Unconjugated
Gene
Igf1r
Gene Alias
A330103N21Rik; CD221; D930020L01; hyft; IGF-1 receptor; Igf1r; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3480
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This antibody has specificity for Human IGF1R/CD221
- IGF1R (Insulin-like Growth Factor1 Receptor) is a receptor tyrosine kinase that mediates actions of insulin-like growth factor 1 (IFG1)
- It binds IGF1 with high affinity and IGF2/insulin with lower affinity
- Activated IGF1R is involved in cell growth and survival control
- IGF1R is crucial for tumor transformation and survial of malignant cells
- Ligand binding activates the receptor kinase and leads to receptor autophosphorylation and tyrosines phosphorylation of multiple substrates that function as signaling adapter proteins.