PIMA530536

Factor XI Monoclonal Antibody (2B7E12F8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA530536-Each-of-1 In Stock ₹ 32,485.00

PIMA530536 - Each of 1

₹ 32,485.00

In Stock

Quantity

1

Base Price: ₹ 32,485.00

GST (18%): ₹ 5,847.30

Total Price: ₹ 38,332.30

Antigen

Factor XI

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P03951

Gene Symbols

F11

Immunogen

Recombinant Human FXI protein (Met1-Val625)

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA

Clone

2B7E12F8

Conjugate

Unconjugated

Gene

F11

Gene Alias

1600027G01Rik; AI503996; Cf11; Coagulation factor XI; Coagulation factor XIa heavy chain; Coagulation factor XIa light chain; F11; FXI; LRRGT00086; plasma thromboplastin antecedent; PTA

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

2160

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • This antibody has specificity for Human FXI/F11/Factor XI
  • This gene encodes coagulation factor XI of the blood coagulation cascade
  • This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds
  • During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds
  • This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX
  • Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.