PIMA530538

IL17RB Monoclonal Antibody (09), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA530538-Each-of-1 In Stock ₹ 32,485.00

PIMA530538 - Each of 1

₹ 32,485.00

In Stock

Quantity

1

Base Price: ₹ 32,485.00

GST (18%): ₹ 5,847.30

Total Price: ₹ 38,332.30

Antigen

IL17RB

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q9NRM6

Gene Symbols

IL17RB

Immunogen

Recombinant Human IL17BR/IL17RB/IL-17 Receptor B Protein (Met1-Gly289)

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

ELISA

Clone

09

Conjugate

Unconjugated

Gene

IL17RB

Gene Alias

CRL4; cytokine receptor CRL4; cytokine receptor-like 4; ecotropic viral integration site 27; EVI27; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B; IL-17B receptor; IL17BR; IL-17ER; Il17rb; IL-17RB; IL17RH1; IL-17Rh1; IL-20; interleukin 17 receptor B; interleukin 17 receptor homolog 1; interleukin 17B receptor; interleukin-17 receptor B; Interleukin-17B receptor; MGC138900; MGC138901; MGC5245; UNQ2501/PRO19612; ZCYTO7

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

55540

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • This antibody has specificity for Human IL17BR/IL17RB/IL-17 Receptor B
  • Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified
  • These are termed as IL-17B, IL-17C (1) and IL-17E
  • IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth
  • IL-17B, C, and E like IL-17 are able to induce proinflammatory responses
  • However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist
  • Receptor for IL-17B and IL-17E has been independently isolated and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively
  • IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8
  • IL-17Rh1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.