Interferon alpha-2 Recombinant Rabbit Monoclonal Antibody (001), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA530656-Each-of-1 | In Stock | ₹ 41,919.00 |
PIMA530656 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,919.00
GST (18%): ₹ 7,545.42
Total Price: ₹ 49,464.42
Antigen
Interferon alpha-2
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P01563
Gene Symbols
IFNA2
Immunogen
Recombinant Human Interferon alpha 2/IFNA2 Protein (Cys24-Glu188)
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA
Clone
001
Conjugate
Unconjugated
Gene
IFNA2
Gene Alias
alpha-2a interferon; Ifa2; IFNA; IFN-a; IFNA 2; Ifna2; IFNA2A; IFNA2B; IFNA2C; IFN-alpha 1b; IFN-alpha-1/13; IFN-alpha-2; IFN-alphaA; INFA2; interferon alpha 1b; interferon alpha 2; interferon alpha 2a; interferon alpha 2b; interferon alpha A; interferon alpha family, gene 2; interferon alpha-2; Interferon alpha-A; interferon alpha-D; interferon, alpha 2; Interferon-alpha II; leIF A; leIF D; RP11-354P17.2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3440
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This antibody has specificity for Human Interferon alpha 2/IFNA2
- IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates
- The interaction of IFN-alpha with its receptor component result in the activation of a number of signaling pathways which are mainly involved in innate immune response against viral infection
- In humans, the gene for IFN alpha is located on on chromosome 9
- The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms
- Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species
- IFN alpha is produced primarily by plasmacytoid dendritic cells, is a potent component of the anti-viral innate immune response and modulates adaptive immunity
- Diseases associated with the dysfunction of IFN alpha include Hepatitis C and Hepatitis.