SETD7 Recombinant Rabbit Monoclonal Antibody (001), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA530872-Each-of-1 | In Stock | ₹ 41,385.00 |
PIMA530872 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,385.00
GST (18%): ₹ 7,449.30
Total Price: ₹ 48,834.30
Antigen
SETD7
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q8WTS6
Gene Symbols
Setd7
Immunogen
Recombinant Human SETD7/SET7/9 protein (Asp2-Lys366)
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA
Clone
001
Conjugate
Unconjugated
Gene
Setd7
Gene Alias
1600028F23Rik; FLJ21193; H3-K4 methyltransferase; H3-K4-HMTase; H3-K4-HMTase SETD7; H3K4MT; Histone H3-K4 methyltransferase SETD7; histone H3-lysine 4-specific methyltransferase; histone-lysine N-methyltransferase SETD7; Kiaa1717; KMT7; lysine N-methyltransferase 7; mKIAA1717; OTTHUMP00000220049; SET domain containing (lysine methyltransferase) 7; SET domain containing 7, histone lysine methyltransferase; SET domain containing 7, lysine methyltransferase; SET domain containing lysine methyltransferase 7; SET domain-containing protein 7; Set7; Set7/9; SET9; Setd7
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
80854
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This antibody has specificity for Human SETD7/SET7/9
- Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3
- H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation
- Plays a central role in the transcriptional activation of genes such as collagenase or insulin
- Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription
- Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins
- Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II
- Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation
- [UniProt]