AMICA Monoclonal Antibody (06), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA530943-Each-of-1 | In Stock | ₹ 32,485.00 |
PIMA530943 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,485.00
GST (18%): ₹ 5,847.30
Total Price: ₹ 38,332.30
Antigen
AMICA
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q86YT9
Gene Symbols
JAML
Immunogen
Recombinant Human JAML/AMICA1 Protein (Met1-Leu275)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Applications
ELISA
Clone
06
Conjugate
Unconjugated
Gene
JAML
Gene Alias
adhesion molecule AMICA; adhesion molecule interacting with CXADR antigen 1; adhesion molecule, interacts with CXADR antigen 1; AMICA; Amica1; Crea7; CREA7-1; CREA7-4; Dendritic cell-specific protein CREA7; Dendritic cell-specific protein CREA7-1; dendritic-cell specific protein Crea7; dendritic-cell specific protein CREA7-1; dendritic-cell specific protein CREA7-4; Gm638; Jaml; junction adhesion molecule like; junctional adhesion molecule-like; mCrea7; UNQ722/PRO1387
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
120425
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- This antibody has specificity for Human JAML/AMICA1
- AMICA transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells
- The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair
- Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases
- It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair
- It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR.