J Chain Recombinant Rabbit Monoclonal Antibody (027), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA530945-Each-of-1 | In Stock | ₹ 43,031.50 |
PIMA530945 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,031.50
GST (18%): ₹ 7,745.67
Total Price: ₹ 50,777.17
Antigen
J Chain
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P01591
Gene Symbols
JCHAIN
Immunogen
Recombinant Human IGJ protein (Gln23-Asp159)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA
Clone
027
Conjugate
Unconjugated
Gene
JCHAIN
Gene Alias
9530090F24Rik; AI323815; IGCJ; Igj; IgJ chain; immunoglobulin J chain; immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides; immunoglobulin joining chain; immunoglobulin joining gene (not J region); J chain; Jch; JCHAIN; Joining chain of multimeric IgA and IgM
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3512
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This antibody has specificity for Human IGJ
- J chain is a small glycopeptide and is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins
- J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells
- J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsil and lymph node
- B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.