PIMA531117

TEM7 Monoclonal Antibody (04), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA531117-Each-of-1 In Stock ₹ 32,485.00

PIMA531117 - Each of 1

₹ 32,485.00

In Stock

Quantity

1

Base Price: ₹ 32,485.00

GST (18%): ₹ 5,847.30

Total Price: ₹ 38,332.30

Antigen

TEM7

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q8IUK5

Gene Symbols

PLXDC1

Immunogen

Recombinant Human TEM7/PLXDC1 Protein (Met1-Thr426)

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA

Clone

04

Conjugate

Unconjugated

Gene

PLXDC1

Gene Alias

2410003I07Rik; ADP-ribosylation factor-like 12; AI848450; Arl12; DKFZp686F0937; FLJ36270; FLJ45632; plexin domain containing 1; plexin domain-containing protein 1; PLXDC1; TEM3; TEM7; TEM7 related; tumor endothelial marker 3; Tumor endothelial marker 7; tumor endothelial marker7

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

57125

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • This antibody has specificity for Human TEM7/PLXDC1
  • Recently, using SAGE (Serial Analysis of Gene Expression) technology, St
  • Croix et al, have identified 46 genes, whose expression is specifically elevated in tumor-associated endothelium
  • Nine of these genes were prominently expressed only in tumor endothelial cells (EC), but were absent or barely detectable in normal ECs, and named as Tumor Endothelial Markers (TEMs, TEM 1-9)
  • TEM7 (Tumor endothelial marker 7) transcripts are specifically expressed in the endothelium of colorectal cancer, primary cancers of lung, pancreas, breast, and brain
  • TEM7 is expressed specifically in endothelium of these cancers, whether primary or metastasis
  • The other six members of this family (TEM1, 3, 4, 5, 8, and 9) also show similar expression pattern in lung and brain tumors, and liver metastasis
  • Since most of the genes expressed differentially in tumor endothelium are also expressed during angiogenesis, these newly discovered genes might provide important resources for basic and clinical studies of human angiogenesis.