PIMA531270

ACE2 Monoclonal Antibody (04), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA531270-Each-of-1 In Stock ₹ 32,485.00

PIMA531270 - Each of 1

₹ 32,485.00

In Stock

Quantity

1

Base Price: ₹ 32,485.00

GST (18%): ₹ 5,847.30

Total Price: ₹ 38,332.30

Antigen

ACE2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q5EGZ1

Gene Symbols

ACE2

Immunogen

Recombinant Rat ACE2/Angiotensin-Converting Enzyme 2 Protein (Met1-Thr740)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Rat

Product Type

Antibody

Applications

ELISA

Clone

04

Conjugate

Unconjugated

Gene

ACE2

Gene Alias

2010305L05Rik; ACE 2; Ace2; ACEH; ACE-related carboxypeptidase; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin I converting enzyme 2; angiotensin-converting enzyme 2; Angiotensin-converting enzyme homolog; anigotensin I converting enzyme 2; anigotensin-converting enzyme-related carboxypeptidase; metalloprotease MPROT15; peptidyl-dipeptidase A; Processed angiotensin-converting enzyme 2; renal angiotensin-converting enzyme 2; UNQ868/PRO1885

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

302668

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • This antibody has specificity for Rat ACE2/Angiotensin-Converting Enzyme 2
  • Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology
  • In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis
  • Recently
  • ACE2 has also been shown to be a functional receptor of the SARS coronavirus
  • The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII
  • While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.