PIMA531354

RON Monoclonal Antibody (CL0463), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA531354-Each-of-1 In Stock ₹ 49,884.50

PIMA531354 - Each of 1

₹ 49,884.50

In Stock

Quantity

1

Base Price: ₹ 49,884.50

GST (18%): ₹ 8,979.21

Total Price: ₹ 58,863.71

Antigen

RON

Classification

Monoclonal

Concentration

0.7 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q04912

Gene Symbols

MST1R

Immunogen

Recombinant protein corresponding to Human MST1R

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

CL0463

Conjugate

Unconjugated

Gene

MST1R

Gene Alias

CD136; Cdw136; c-met-related tyrosine kinase; friend virus susceptibility 2; Fv2; Fv-2; macrophage stimulating 1 receptor; macrophage stimulating 1 receptor (c-met-related tyrosine kinase); macrophage-stimulating protein receptor; Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain; MSP receptor; Mst1r; MST1R variant RON30; MST1R variant RON62; p185-Ron; protein tyrosine kinase 8; Protein-tyrosine kinase 8; PTK8; PTK8 protein tyrosine kinase 8; receptor protein tyrosine kinase, c-met-related; RON; RON variant E2E3; Stem cell-derived tyrosine kinase; STK

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4486

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Immunogen sequence: EDPVVLSISP NCGYINSHIT ICGQHLTSAW HLVLSFHDGL RAVESRCERQ LPEQQLCRLP EYVVRDPQGW VAGNLSARGD GAAGFTLPGF RFLPPPHPPS ANLVPLKP MST1R (RON) is a receptor tyrosine kinase involved in cell proliferation and motility
  • The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits
  • Ligand binding results in tyrosine phosphorylation of the beta chain
  • In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period
  • The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers
  • MST1R/Ron expression has been documented in many normal human tissues
  • ESTs have been isolated from several tissue libraries, including normal colon, mouth, prostate, and testis and cancerous colon, prostate, stomach, and uteru.