ROR2 Monoclonal Antibody (CL5950), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA531429-Each-of-1 | In Stock | ₹ 52,376.50 |
PIMA531429 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,376.50
GST (18%): ₹ 9,427.77
Total Price: ₹ 61,804.27
Antigen
ROR2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q01974
Gene Symbols
ROR2
Immunogen
Synthetic peptide corresponding to Human ROR2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunohistochemistry
Clone
CL5950
Conjugate
Unconjugated
Gene
ROR2
Gene Alias
BDB; BDB1; mRor2; neurotrophic tyrosine kinase receptor-related 2; neurotrophic tyrosine kinase, receptor related 2; neurotrophic tyrosine kinase, receptor-related 2; NTRKR2; receptor tyrosine kinase like orphan receptor 2; receptor tyrosine kinase-like orphan receptor 2; ROR2; Tyrosine-protein kinase transmembrane receptor ROR2
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
4920
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Immunogen sequence: ADRAALLSEG ADDTQNAPE ROR2 (receptor tyrosine kinase-like orphan receptor 2) is a type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors
- It is thought to be involved in the early formation of the chondrocytes and cartilage and growth plate development
- This Type I membrane protein is expressed at high levels during early embryonic development
- The expression levels drop strongly around day 16 and there are only very low levels in adult tissues
- Defects in ROR2 are a cause of brachydactyly type B1 (BDB1)
- BDB1 is an autosomal dominant skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails
- In BDB1 the middle phalanges are short but in addition the terminal phalanges are rudimentary or absent
- Both fingers and toes are affected
- The thumbs and big toes are usually deformed
- Defects in ROR2 are a cause of recessive Robinow syndrome (RRS)
- RRS is an autosomal disorder characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly and a dysmorphic facial appearance
- The protein contains 1 frizzled (FZ) domain, 1 immunoglobulin-like C2-type domain, and 1 kringle domain.