PIMA531631

Aquaporin 2 Monoclonal Antibody (5B6B12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA531631-Each-of-1 In Stock ₹ 49,350.50

PIMA531631 - Each of 1

₹ 49,350.50

In Stock

Quantity

1

Base Price: ₹ 49,350.50

GST (18%): ₹ 8,883.09

Total Price: ₹ 58,233.59

Antigen

Aquaporin 2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

P41181

Gene Symbols

Aqp2

Immunogen

Purified recombinant fragment of human AQP2 (AA: 149-271) expressed in E. coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Western Blot

Clone

5B6B12

Conjugate

Unconjugated

Gene

Aqp2

Gene Alias

ADH water channel; AQP 2; AQP CD; Aqp2; AQP-2; AQPCD; AQP-CD; aquaporin 2; aquaporin 2 (collecting duct); Aquaporin CD; Aquaporin2; aquaporin-2; Aquaporin-CD; Aquaporine 2; collecting duct water channel protein; cph; jpk; MGC34501; Water channel protein for renal collecting duct; water-channel aquaporin 2; WCH CD; WCHCD; WCH-CD

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

359

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA5-31631 has been tested in indirect ELISA
  • Aquaporin 2 (AQP2) is a hormonally regulated water channel located in the renal collecting duct
  • Mutations in the AQP2 gene cause hereditary nephrogenic diabetes insipidus in humans
  • A vasopressin induced cAMP increase results in the phosphorylation of AQP2 at serine-256 and its translocation from the intracellular vesicles to the apical membrane of principal cells
  • Recently, serine-261 has been identified as a novel phosphorylation site on AQP2 and levels of phosphorylated S261 have been shown to decrease with vasopressin treatment suggesting its involvement in vasopressin-dependent AQP2 trafficking.