PIMA531775
IGHA1 Monoclonal Antibody (7D12C5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA531775-Each-of-1 | In Stock | ₹ 49,350.50 |
PIMA531775 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,350.50
GST (18%): ₹ 8,883.09
Total Price: ₹ 58,233.59
Antigen
IGHA1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P01876
Gene Symbols
IGHA1
Immunogen
Purified recombinant fragment of human IghA1 (AA: 207-353) expressed in E. coli.
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone
7D12C5
Conjugate
Unconjugated
Gene
IGHA1
Gene Alias
IgA1; IGHA1; IGHA2; immunoglobulin heavy constant alpha 1; immunoglobulin heavy constant alpha 2 (A2m marker)
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
3493
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA5-31775 has been tested in indirect ELISA
- Constant region of immunoglobulin heavy chains
- Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes
- In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells
- Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268)
- The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain
- Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen
- The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)
- Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915)
- [UniProt]