PXR Monoclonal Antibody (6H11D8), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA531809-Each-of-1 | In Stock | ₹ 49,350.50 |
PIMA531809 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,350.50
GST (18%): ₹ 8,883.09
Total Price: ₹ 58,233.59
Antigen
PXR
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
O75469
Gene Symbols
NR1I2
Immunogen
Purified recombinant fragment of human NR1I2 (AA:1-142) expressed in E. coli.
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Western Blot
Clone
6H11D8
Conjugate
Unconjugated
Gene
NR1I2
Gene Alias
BXR; mPXR; Nr1i2; Nuclear receptor subfamily 1 group I member 2; nuclear receptor subfamily 1, group 1, member 2; nuclear receptor subfamily 1, group I, member 2; ONR 1; ONR1; orphan nuclear receptor PAR1; Orphan nuclear receptor PXR; PAR; PAR 1; PAR 2; PAR q; PAR1; PAR2; PARq; pregnane X nuclear receptor variant 2; Pregnane X receptor; pregnane X receptor (nuclear receptor sub family 1, group I, member 2); PRR; PXR; PXR.1; PXR.2; PXR1; SAR; Steroid and xenobiotic receptor; SXR
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
8856
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA5-31809 has been tested in indirect ELISA
- This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain
- The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR
- It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin
- Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG translation initiation codon, have been described for this gene
- Additional transcript variants exist, however, they have not been fully characterized.