DARPP-32 Recombinant Rabbit Monoclonal Antibody (SU0329), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532113-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532113 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
DARPP-32
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q60829, Q6J4I0, Q9UD71
Gene Symbols
Ppp1r1b
Immunogen
Recombinant protein within Human DARPP32 aa 1-94
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Western Blot, Immunohistochemistry, Western Blot
Clone
SU0329
Conjugate
Unconjugated
Gene
Ppp1r1b
Gene Alias
AU040756, DARPP32, DARPP-32, dopamine- and cAMP-regulated neuronal phosphoprotein, dopamine and cAMP-regulated neuronal phosphoprotein 32, dopamine- and cAMP-regulated phosphoprotein DARPP-32, FLJ20940, IPPD, neuronal phosphoprotein DARPP-32, OTTHUMP00000164275, OTTHUMP00000164276, Ppp1r1b, PPR1B, protein pho, protein phosphatase 1 regulatory inhibitor subunit 1B, protein phosphatase 1 regulatory subunit 1B, protein phosphatase 1, regulatory (inhibitor) subunit 1B
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
19049, 360616, 84152
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- DARPP-32 is a dopamine (DA) and AMP-regugated ∽32 kDa phosphoprotein that is associated with dopaminoceptive neurons
- The protein inhibits Protein Phosphatase I when it is phosphorylated on Thr34
- In contrast, when DARPP-32 is phosphorylated on Thr75 the protein acts as an inhibitor of PKA
- Phosphorylation of DARPP-32 is thought to play a critical role in the regugation of dopaminergic neurotransmission
- In addition, the activity of DARPP-32 is also thought to play important roles in the actions of alcohol, caffeine and Prozac®.