PIMA532123

TrkA Recombinant Rabbit Monoclonal Antibody (SU0354), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532123-Each-of-1 In Stock ₹ 48,282.50

PIMA532123 - Each of 1

₹ 48,282.50

In Stock

Quantity

1

Base Price: ₹ 48,282.50

GST (18%): ₹ 8,690.85

Total Price: ₹ 56,973.35

Antigen

TrkA

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P04629, P35739, Q3UFB7

Gene Symbols

Ntrk1

Immunogen

Synthetic peptide within Human TrkA aa 747-796

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SU0354

Conjugate

Unconjugated

Gene

Ntrk1

Gene Alias

C80751, DKFZp781I14186, EC 2.7.10.1, gp140trk, high affinity nerve growth factor receptor, kinase TrkA, MTC, neurotrophic receptor tyrosine kinase 1, Neurotrophic tyrosine kinase receptor type 1, neurotrophic tyrosine kinase, receptor, type 1, Ntrk1, Oncogene TRK, p140-TrkA, Slow nerve growth factor receptor, Tkr, TRK, TRK1, TRK1-transforming tyrosine kinase protein, Trka, Trk-A, TrkA neurotrophin receptor, trkA proto-oncogene receptor, tropomyosin-related kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

18211, 4914, 59109

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system
  • TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway
  • The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes
  • Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.