PIMA532228

TOP1 Recombinant Rabbit Monoclonal Antibody (SC69-03), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532228-Each-of-1 In Stock ₹ 53,088.50

PIMA532228 - Each of 1

₹ 53,088.50

In Stock

Quantity

1

Base Price: ₹ 53,088.50

GST (18%): ₹ 9,555.93

Total Price: ₹ 62,644.43

Antigen

TOP1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P11387, Q04750

Gene Symbols

Top1

Immunogen

Synthetic peptide within Human TOP1 aa 1-49

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SC69-03

Conjugate

Unconjugated

Gene

Top1

Gene Alias

Ab2-086, AI467334, D130064I21Rik, DNA topoisomerase 1, DNA topoisomerase I, RP3-511B24.2, TOP1, Top-1, TOPI, topoisomerase (DNA) I, type I DNA topoisomerase

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

21969, 7150

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription
  • This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA
  • This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.