PIMA532337

Cytokeratin 4 Recombinant Rabbit Monoclonal Antibody (SN2001), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532337-Each-of-1 In Stock ₹ 47,481.50

PIMA532337 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

Cytokeratin 4

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P19013, Q6IG00

Gene Symbols

KRT4

Immunogen

Synthetic peptide within Human Cytokeratin 4 aa 1-50

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SN2001

Conjugate

Unconjugated

Gene

KRT4

Gene Alias

57kd keratin, 57kDa keratin, AW108092, cb59, CK4, CK-4, CYK4, cytokeratin, cytokeratin 4, cytokeratin-4, Cytoskeletal 57 kDa keratin, etID20321.6, intermediate filament protein, K4, Kb4, keratin 4, keratin 4, type II, keratin 8, keratin complex 2, basic, gene 4, keratin, type II cytoskeletal 4, Keratin-4, Krt-2.4, Krt2-4, Krt4, krt4 {ECO:0000250, krt4 protein, krt8, type II basic cytokeratin, type II keratin Kb4, type-II keratin Kb4, UniProtKB:P19013}, WSN1, wu:fa91a11, wu:fd19e09, wu:fl23c09, zf-K8

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

315323, 3851

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides
  • They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4
  • 9-7
  • 8
  • The individual human cytokeratins are numbered 1 to 20
  • The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium
  • Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies
  • The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.