PIMA532350

RelB Recombinant Rabbit Monoclonal Antibody (SD07-39), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532350-Each-of-1 In Stock ₹ 47,481.50

PIMA532350 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

RelB

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q01201

Gene Symbols

RELB

Immunogen

Synthetic peptide within Human RelB aa 1-50

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SD07-39

Conjugate

Unconjugated

Gene

RELB

Gene Alias

avian reticuloendotheliosis viral (v-rel) oncogene related B, IREL, I-REL, OTTHUMP00000221313, rel b, RELB, REL-B, RELB proto-oncogene, NF-kB subunit, shep, transcription factor RelB, v-rel avian reticuloendotheliosis viral oncogene homolog B, v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3), v-rel reticuloen, v-rel reticuloendotheliosis viral oncogene homolog B, v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5971

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • The NFkB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein
  • The DNAbinding subunit is functionally related to c-Rel p75 and Rel B p68
  • The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105
  • A second protein designated p52 (previously referred to as p49) has been identified that can act as an alternative NFkB subunit
  • Rel B does not bind with high affinity to NFkB sites, but heterodimers between Rel B and p50 bind with an affinity comparable to that of p50 NFkB homodimers
  • However, Rel B/p50 heterodimers, in contrast to NFkB heterodimers, transactivates transcription of promotors containing kB binding sites.