HSPB8 Recombinant Rabbit Monoclonal Antibody (JJ08-53), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532421-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532421 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
HSPB8
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q9EPX0, Q9JK92, Q9UJY1
Gene Symbols
HSPB8
Immunogen
Synthetic peptide within Human Hsp20 aa 1-50
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
JJ08-53
Conjugate
Unconjugated
Gene
HSPB8
Gene Alias
Alpha-crystallin C chain, AU018630, AW413033, CMT2L, Cryac, crystallin, alpha C, D5Ucla4, DHMN 2, DHMN2, E2IG1, E2-induced gene 1 protein, H11, H11K, heat shock 22kDa protein 8, heat shock 27kDa protein 8, Heat shock protein, heat shock protein 8, heat shock protein B8, heat shock protein beta-8, heat shock protein family B (small) member 8, HMN 2, HMN2, HMN2A, HSB8, HSP, HSP20-like, Hsp22, HSPB 8, Hspb8, OTTHUMP00000239768, PP1629, Protein kinase H11, small stress protein-like protein HSP22
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
113906, 26353, 80888
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule
- The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy
- Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.