PSMB8 Recombinant Rabbit Monoclonal Antibody (JB54-32), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA534676-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA534676 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
PSMB8
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P28062
Gene Symbols
Psmb8
Immunogen
Recombinant protein within Human Proteasome 20S LMP7 aa 160-276
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
JB54-32
Conjugate
Unconjugated
Gene
Psmb8
Gene Alias
ALDD; D6S216; D6S216E; DAAP-57C1.3; JMP; large multifunctional protease 7; Lmp7; Lmp-7; low molecular mass polypeptide 7; low molecular mass protein 7; low molecular weight protein 7; macropain subunit C13; Mc13; MC13 (LMP7); MGC1491; multicatalytic endopeptidase complex subunit C13; NKJO; OTTHUMP00000029420; OTTHUMP00000029421; OTTHUMP00000062981; protease component C13; proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7); proteasome (prosome, macropain) subunit, beta type, 8; proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7); proteasome catalytic subunit 3i; proteasome component C13; proteasome subunit beta 5i; proteasome subunit beta 8; proteasome subunit beta type 8; proteasome subunit beta type-8; Proteasome subunit beta-5i; proteasome subunit MC13; proteasome subunit Y2; proteasome-related gene 7; proteosome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7); proteosome beta 8 subunit; PSMB5i; Psmb8; Really interesting new gene 10 protein; Ring10; Y2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5696
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form
Liquid
Related Products
Description
- Positive Control: U937, Rat epididymis tissue, human liver tissue, human kidney tissue, mouse small intestine tissue, A431, HUVEC, Daudi
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure
- The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits
- Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway
- An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides
- This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit
- This gene is located in the class II region of the MHC (major histocompatibility complex)
- Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome
- Proteolytic processing is required to generate a mature subunit
- Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit.