PIMA534753

SUV39H2 Recombinant Rabbit Monoclonal Antibody (JG36-55), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA534753-Each-of-1 In Stock ₹ 47,481.50

PIMA534753 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

SUV39H2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q9H5I1

Gene Symbols

SUV39H2

Immunogen

Synthetic peptide within Human SUV39H2 aa 361-410

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

JG36-55

Conjugate

Unconjugated

Gene

SUV39H2

Gene Alias

4930507K23Rik; AA536750; D030054H19Rik; D2Ertd544e; FLJ23414; H3 K9 HMTase 2; H3-K9-HMTase 2; Histone H3-K9 methyltransferase 2; histone-lysine N-methyltransferase SUV39H2; KMT1; KMT1B; lysine N-methyltransferase 1B; RP11-2K17.2; Su; Su(var)3-9 homolog 2; suppressor of variegation 3-9 homolog 2; suppressor of variegation 3-9 homolog 2 (Drosophila); Suv39h histone methyltransferase; Suv39h2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

79723

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles, store in dark

Form

Liquid

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Description

  • Positive Control: SiHa, A549, mouse testis tissue
  • The murine gene Suv39h2 encodes an H3 histone methyltransferase (HMTase) 59% identical in sequence to mouse Suv39h1
  • During embryogenesis, both proteins overlap in tissue expression, yet Suv39h2 transcripts are restricted to the testes in adult animals
  • Immunolocalization of the Suv39h2 protein during spermatogenesis indicates enrichment at the heterochromatin from the leptotene to the round spermatid stage
  • Moreover, Suv39h2 specifically accumulates with chromatin of the sex chromosomes, which undergo transcriptional silencing during the first meiotic prophase
  • Suv39h2 HMTase may also organize meiotic heterochromatin with the potential for epigenetic imprint to the male germline.