COMT Recombinant Rabbit Monoclonal Antibody (JG39-48), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA534798-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA534798 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
COMT
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P21964
Gene Symbols
Comt
Immunogen
Recombinant protein within COMT aa 11-107
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
JG39-48
Conjugate
Unconjugated
Gene
Comt
Gene Alias
Catechol O-methyltransferase; catecholamine-O-methyltransferase; catechol-O-methyltransferase; catechol-O-methyltransferase 1; catechol-O-methyltransferase isoform; Comt; Comt1; D16Wsu103e; D330014B15Rik; epididymis secretory sperm binding protein Li 98n; HEL-S-98n; OTTHUMP00000197749; OTTHUMP00000197750; testicular tissue protein Li 42
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1312
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form
Liquid
Related Products
Description
- Positive Control: MCF-7, rat testis tissue lysate, mouse testis tissue
- Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine
- This O-methylation results in one of the major degradative pathways of the catecholamine transmitters
- In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease
- COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT)
- The differences between S-COMT and MB-COMT reside within the N-termini
- Several transcript variants are formed through the use of alternative translation initiation sites and promoters.