PIMA534911

HSP701L Monoclonal Antibody (7D1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA534911-Each-of-1 In Stock ₹ 47,481.50

PIMA534911 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

HSP701L

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P34931

Gene Symbols

Hspa1l

Immunogen

Recombinant protein with Human HSPA1L aa 335-639

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

7D1

Conjugate

Unconjugated

Gene

Hspa1l

Gene Alias

heat shock 10kDa protein 1-like; heat shock 70 kDa protein 1-Hom; heat shock 70 kDa protein 1L; Heat shock 70 kDa protein 1-like; Heat shock 70 kDa protein 3; heat shock 70 kDa-like protein 1; heat shock 70kD protein-like 1; heat shock 70kDa protein 1-like; Heat shock protein; heat shock protein 1-like; Heat shock protein 70-1l; heat shock protein cognate 70, testis; heat shock protein family A (Hsp70) member 1 like; heat shock-related protein hsc70t; Hsc70t; HSP70.3; HSP70-1L; Hsp70-3; HSP70-HOM; HSP70T; Hspa1l; hum70t; inducible heat shock protein 70; Msh5; Spermatid-specific heat shock protein 70

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3305

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles, store in dark

Form

Liquid

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Description

  • Positive Control: A549, mouse testis tissue, rat testis tissue
  • In response to adverse changes in their environment, cells from many organisms increase the expression of a class of proteins referred to as heat shock proteins
  • One class of stress proteins, termed the &quotesmall heat shock proteins&quote is comprised of a diverse group of proteins from approximately15 to >30 kDa, with a single form found in yeast and human cells and multiple related forms found in higher plants
  • A direct relationship between elevated strwess protein expression and neoplasia has been suggested from studies on estrogen-induced proteins in breast cancer cells
  • In addition, Hsp27 exhibits rapid increased phosphorylation in response to various mitogens, tumor promoter (e
  • g
  • phorbol esters) and calcium ionophores
  • The expression of a 24 kDa protein was shown to correlate with steroid hormone receptor in cell lines, organs, and tumors
  • The 24 kDa estrogen-induced protein was found to be expressed at high levels in carcinoma of the breast
  • Another study has suggested that levels of the Hsp27 correlate with endometrial adenocarcinomas
  • Interestingly, the regulation of human Hsp27 by estrogens and heat shock is reminiscent of the ecdysteroid and heat shock activation of the drosophila Hsp20 genes.