Mast Cell Chymase Recombinant Rabbit Monoclonal Antibody (ARC0614), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA535118-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA535118 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Mast Cell Chymase
Classification
Monoclonal
Concentration
1.5 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P21844, P23946, P50339
Gene Symbols
CMA1
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 148-247 of human Mast Cell Chymase (CMA1) (CMA1) (P23946)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
ARC0614
Conjugate
Unconjugated
Gene
CMA1
Gene Alias
alpha-chymase; Chymase; chymase 1; chymase 1 preproprotein transcript E; chymase 1 preproprotein transcript I; chymase 1, mast cell; chymase, heart; chymase, mast cell; CMA1; CYH; CYM; mast cell; Mast cell chymase 1; mast cell protease 3; Mast cell protease 5; mast cell protease I; Mast cell protease III; MCP3P; Mcp5; Mcp-5; Mcpt3; Mcpt5; MCT1; mMCP-5; rMCP-3; rMCP-5; rMCP-III
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1215, 17228, 25627
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Immunogen sequence: GWGRTGVLKP GSDTLQEVKL RLMDPQACSH FRDFDHNLQL CVGNPRKTKS AFKGDSGGPL LCAGVAQGIV SYGRSDAKPP AVFTRISHYR PWINQILQAN This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1
- It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides
- In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II
- Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure
- Thus, this gene product is a target for cardiovascular disease therapies
- This gene maps to 14q11
- 2 in a cluster of genes encoding other proteases.