Synuclein alpha/beta Recombinant Rabbit Monoclonal Antibody (ARC1181), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA535604-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA535604 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Synuclein alpha/beta
Classification
Monoclonal
Concentration
1.35 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O55042, P37377, P37840, Q16143, Q63754, Q91ZZ3
Gene Symbols
Snca, SNCB
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human alpha + beta Synuclein (P37840)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
ARC1181
Conjugate
Unconjugated
Gene
Snca
Gene Alias
AI838531; alphaSYN; alpha-synuclein; betaSYN; Beta-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Phosphoneuroprotein 14; PNP 14; SNCA; Sncb; Syn; synuclein alpha; synuclein alpha-140; synuclein beta; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor); synuclein, beta
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
104069, 113893, 20617, 29219, 6620, 6622
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Immunogen sequence: MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals
- In vertebrates they are encoded by three different genes
- Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's PD) and breast cancer
- In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid
- In PD, an alpha synuclein accumulates in Lewy bodies
- An allele of alpha synuclein has been linked to many familial cases of PD
- In breast cancer increased expression of gamma synuclein correlates with the disease progression
- Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.